Understanding metastasis in multiple myeloma
Multiple myeloma is an incurable cancer that is diagnosed in approximately 1,700 people in Australia every year.
Like breast cancer and prostate cancer, multiple myeloma spreads, or metastasises, throughout the bone marrow. Patients with more metastatic disease tend to have very poor survival.
In this project, the team will investigate how the cancer cells spread through the body, using molecular biology approaches in combination with a robust mouse model of myeloma and transcriptomic analysis of patient tumour cells to determine the genes that are responsible for myeloma tumour dissemination.
The aim is to define the mechanisms responsible for tumour dissemination in multiple myeloma and l identify novel therapeutic targets.
Project Leaders
This project is funded by Cancer Australia, Cancer Council SA Beat Cancer Project, Cure Cancer Australia and Leukaemia Foundation Australia
SAHMRI is located on Kaurna Country. We pay respects to the Kaurna people of the Adelaide Plains and to all Aboriginal and Torres Strait Islander people. We are committed to embracing knowledge and culture as we continue our working journey to incorporate Aboriginal health research across all of our themes and further reconciliation.
Read more"Tirki nguta tappa tangka marninithi"
(Learning and knowledge are the pathway to alter the mind)
- Uncle Lewis Yerloburka O’Brien, Kaurna Elder
